AKI on ESRD?
Hi everyone,
When a patient with ESRD is admitted for the emergency HD due to missing HD, can this patient possibly have acute on chronic renal failure? I thought ESRD is already "end stage" as it is written and the increased Cr and other abnormal lab values are due to "missed HD" not because of worsening the kidney function (and my understanding of "end stage" is it cannot get any worse). But one of my co-workers usually queries for AKI in such cases based on those abnormal lab values. We asked our physicians and their answers split as well. I'd like to hear your opinions, please.
Thank you,
Misato
When a patient with ESRD is admitted for the emergency HD due to missing HD, can this patient possibly have acute on chronic renal failure? I thought ESRD is already "end stage" as it is written and the increased Cr and other abnormal lab values are due to "missed HD" not because of worsening the kidney function (and my understanding of "end stage" is it cannot get any worse). But one of my co-workers usually queries for AKI in such cases based on those abnormal lab values. We asked our physicians and their answers split as well. I'd like to hear your opinions, please.
Thank you,
Misato
Comments
I have been advised by clinical advisers that acute kidney injury can't exist in ESRD as the nephrons are not functional. Certainly willing (and eager) to revisit if the renal experts have revisited this topic from a clinical perspective. For that reason, I don't query or expect to see AKI in the setting of ESRD?
Paul Evans, RHIA, CCDS
Jeff
Angela RN BSN CDS
I wouldnt Query for AKI on ESRD
All that is happened is toxins and fluids and electrolytes have accumulated from missing dialysis.
Now there are some stage 5 CKD patients who are on temporary dialysis due to acute insults where they may regain some kidney function and or healing of an intra-renal diagnosis may be expected, and these patients certainly CAN experience AKI while also on dialysis.
However, they were not truely in ESRD, they were in an advanced stage of CKD and had an acute and reversible (hopefully) insult.
Since it is a continnuum, i can see where confusion could occur between what is a very advanced stage 5 and what is a very begging ESRD as the distinction between one or the other could appear some what arbitrary. There is a lab and uop criteria but i suppose it is possible for some very early or recently diagnosed "ESRD" requiring dialysis to have some small tiny filtering reserve capacity that could be acutely impacted and this may be why some of your doctors are split on the issue.
Here is the thing, if an freshly diagnosis beginning phase ESRD patient with some tiny amount of renal reserves left did have an acute episode....it certainly would have nothing to do with skipping dialysis. It would be from an infection or trauma or dehydration or shock or something.
Missing dialysis is just...missing dialysis and doesn't turn a chronic diagnosis into an acute one in and of itself.